I was diagnosed with CIN2 in 2018 and since then I'm constantly looking for new studies and statistics regarding the rates of regression, persistence and progression of precancerous lesions.
I came across a study that extrapolated cytological data from 3,160 women who participated in 36 studies between 1973 to 2016.
I came across a study that extrapolated cytological data from 3,160 women who participated in 36 studies between 1973 to 2016.
The pooled results were as follows:
- 50% regressed
- 32% persisted
- 18% progressed
- 60% regressed
- 23% persisted
- 11% progressed
During the 24 months of follow-up, none of these women's lesions progressed to cervical cancer.
Keep in mind that regression doesn't necessarily mean complete clearance of the virus in this study. Regression was defined as either the absence of lesions, or the regression to CIN1.
Researchers concluded that active surveillance of CIN2 lesions is an acceptable outcome for patients who want to avoid invasive and risk-prone high-grade cervical dysplasia treatments such as the LEEP and conization procedures.
It is recommended patients remain vigilant about getting pap smears and colposcopies every 6 months should they choose active surveillance over treatment.
This study was overseen by Dr. Maria Kyrgiou, of the Imperial College of London.
Source: MedPage and BMJ
Keep in mind that regression doesn't necessarily mean complete clearance of the virus in this study. Regression was defined as either the absence of lesions, or the regression to CIN1.
Researchers concluded that active surveillance of CIN2 lesions is an acceptable outcome for patients who want to avoid invasive and risk-prone high-grade cervical dysplasia treatments such as the LEEP and conization procedures.
It is recommended patients remain vigilant about getting pap smears and colposcopies every 6 months should they choose active surveillance over treatment.
This study was overseen by Dr. Maria Kyrgiou, of the Imperial College of London.
Source: MedPage and BMJ
